How do you optimize jQuery performance for large DOM structures?

Optimize jQuery performance by minimizing DOM queries, caching selectors, batching DOM updates, and avoiding unnecessary reflows/repaints.

In large DOM applications, jQuery performance bottlenecks usually arise from repeated DOM traversal and manipulation. Each selector query like $('#id') or $('.class') triggers DOM search operations. Instead, caching selectors reduces lookup cost. Batch DOM updates using document fragments or string concatenation before insertion. Avoid layout thrashing by separating read and write operations. Also, prefer delegated events to reduce event handler count. Use efficient selectors (IDs over classes, avoid deep nesting).